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Course Synopses
C109-9 General Year I Chemistry
Atoms, molecules and ions. Physical behaviour of gases. The electronic structure of atoms. The periodic table and the properties of elements. Chemical bonding. Liquids and solids. Solutions. Spontaneity of reactions. Chemical equilibria, rates of reactions, precipitation reactions, acids and bases. Oxidation and reduction. Qualitative analysis of cations and anions.
C214-4 Inorganic Year II Chemistry (Pre-requisite: C109)
Basic nucleus structure, electronic structure of atoms, chemistry of halogens. Periodic properties of elements. Chemistry of alkali metals and alkaline earth metals. Bonding and structure, solid state.
4 Lectures per week, one semester or 2 lectures per week, both semesters
C215-5 Inorganic Year II Chemistry for Non-Majors (Pre-requisite: C109)
Basic nucleus structure, electronic structure of atoms, chemistry of halogens. Periodic properties of elements. Chemistry of alkali metals and alkaline earth metals. Bonding and structure, solid state. Inorganic chemistry practicals.
C224-4 Analytical Year II Chemistry (Pre-requisite: C109)
Error analysis. Review of solution chemistry, oxidation_reduction reactions, pH and buffers. Stoichiometric calculations. Practical work including gravimetric analysis, volumetric analysis, chemical equilibria, emf measurements to determine equilibrium constants. Simple laboratory instrumentation (pH meter, spectrophotometers).
C2133-3 Organic Chemistry for Pharmacy I (Pre-requisite: C109)
Introduction to the following groups of organic compounds, their functional groups and related reactions: alkanes, alkenes, alkynes, conjugated dienes, alkyl halides, alcohols and thiols, ethers, epoxides, sulphides, carbonyl compounds, carboxylic acids, aldehydes, ketones, carboxylic acid derivatives, reactions of carbonyl compounds: alpha substitution and condensation reactions, aliphatic amines
Practical: separation and purification methods for both liquid and solid samples, purity and identity determination methods.
C234-4 Organic Year II Chemistry (Pre-requisite: C109)
Bonding in Organic Compounds. Stereoisomerism: geometric and optical isomerism; racemic forms and their resolution, aliphatic chemistry: nomenclature, properties, preparations and reactions of alkanes, alkenes, alkynes, alkyl halides, alcohols, ethers, carbonyl compounds and amines.
C235-5 Organic Year II Chemistry for Non-Majors (Pre-requisite: C109)
Bonding in Organic Compounds. Stereoisomerism: geometric and optical isomerism; racemic forms and their resolution, aliphatic chemistry: nomenclature, properties, preparations and reactions of alkanes, alkenes, alkynes, alkyl halides, alcohols, ethers, carbonyl compounds and amines. Organic chemistry practicals.
C2143-3 Physical Chemistry for Pharmacy (Pre-requisite: C109)
Properties and behaviour of gases, introduction to thermodynamics, thermodynamic properties of matter, thermo chemistry, entropy, electrochemical equilibrium.
Practical: Laboratory equipment techniques for determination of physical and chemical properties.
C244-4 Physical Year II Chemistry
Empirical properties of gases, behaviour of real gases. Introduction to thermodynamics, thermodynamic properties of matter and the first law, thermochemistry. The second law. Entropy, the direction of natural processes. Electrochemical equilibrium.
C264-4 Spectroscopy Year II Chemistry
Electromagnetic radiation, its interaction with atoms and molecules. Light absorption by molecules, qualitative treatment of the mechanics of light absorption, Eistein coefficients. Molecular symmetry, dipole moments, polarisability, optical activity. General features of experimental methods.
C284-4 Laboratory Year II Experiments in Chemistry (Co-requisites: C214, C234 and C244)
Laboratory techniques and experiments comprising Inorganic Chemistry, Organic Chemistry and Physical Chemistry. Course assessment includes written laboratory reports and a laboratory practical examination held at the end of the course.
C3113-3 Analytical Chemistry for Pharmacy (Pre-requisite: C109)
Volumetric analysis with special reference to weak acids and bases. Back titration determinations. Compleximetric titrations. Redox titrations. Precipitation titrations and gravimetric analysis.
C314-4 Inorganic Year III Chemistry (Pre-requisite: C214)
Solid state chemistry. Coordination chemistry. Chemistry of hydrides. Chemistry of silicon, germanium, tin and lead. Chemistry of nitrogen and phosphorus.
C315 Inorganic Year III Chemistry for non-majors (Pre-requisite - C215 or C214)
Solid state chemistry. Coordination chemistry. Chemistry of hydrides. Chemistry of silicon, germanium, tin and lead. Chemistry of nitrogen and phosphorus. Inorganic chemistry practicals.
C324-4 Analytical Year III Chemistry (Pre-requisite: C224)
Chromatography. Elemental analysis of inorganic and organic compounds. Water quality analysis, analysis of biological samples. Analysis of foodstuff_nutritional values. Literature on Bureau of Standards; policy, objectives and enforcement.
C3133-3 Organic Chemistry for Pharmacy II (Pre-requisite: C213 or C234 or C235)
Aromatic Chemistry: sulphonic acids and derivatives, phenylethylamines, phenylmethanes, naphthalene and polycyclic aromatics.
Heterocyclic Pharmaceuticals: physicochemical properties and origins of compounds containing one or more hetero atom.
Spectroscopic Analysis: introduction to principles of infrared and ultraviolet spectroscopy, their application in structure elucidation and quantitative and qualitative analysis of organic compounds, principles of nuclear magnetic resonance and mass spectroscopy and their application in structure elucidation of organic compounds.
Practical: applications of chromatographic techniques for both qualitative and quantitative analysis, combined spectroscopic analysis for structure elucidation, synthesis and spectroscopic characterisation of simple organic compounds of pharmaceutical interest.
C334-4 Organic Year III Chemistry (Pre-requisite: C234)
Infrared, Ultraviolet, Nuclear Magnetic Resonance and Mass spectrometry. Aromatic Chemistry: benzene and its derivatives; preparations, properties and reactions.
C345-5 Physical Year III Chemistry (Pre-requisite: C244)
General thermodynamics. Chemical thermodynamics: thermochemistry, phase transformations of pure substances, solutions, phase equilibria, chemical equilibria. Chemical kinetics and catalysts: Kinetics of various reactions, reaction mechanisms, kinetic theory of gases, kinetic theories of reaction rates homogeneous catalysis.
C304-4 Physical Methods in Chemistry (Pre-requisite: C234 and C214)
Physical methods of analysis, experimental techniques and instrumentation with special reference to electron paramagnetic resonance, vibrational and rotational spectroscopy, Mossbauer spectroscopy, X-ray crystallography, polarimetry and thermal analysis.
C364-4 Symmetry Spectroscopy and Structure Year III Chemistry (Pre-requisite: C264)
Applications of symmetry in chemistry. Molecular spectroscopy. Structures of solids.
C384-4 Laboratory Year III Experiments in Chemistry (Co-requisites: C314, C334 and C345)
Laboratory experiments comprising Inorganic, Organic and Physical chemistry. Course assessment includes written reports and oral examination held at the end of the course.
C415-5 Inorganic Year IV Chemistry (Pre-requisite: C314)
Electronic and magnetic properties of transition metal complexes. Descriptive chemistry of first transition elements and selected lanthanides. Selected introductory topics in Inorganic chemistry; Organometallic chemistry or Bio-inorganic chemistry or Nuclear chemistry.
C424-4 Analytical Year IV Chemistry (Pre-requisite: C324)
Instrumental methods of analysis: theory and use of standard laboratory instruments. Classical analytical techniques.
C435-5 Organic Year IV Chemistry (Pre-requisite: C334)
Synthesis. Heterocyclic chemistry. Natural products. Carbohydrates. Lipids. Aminoacids and proteins. Nucleic acids. Pericyclic reactions.
C445-5 Physical Year IV Chemistry (Pre-requisite: C345)
Electrochemistry; solutions of electrolytes, equilibrium, electrochemistry, electrochemical kinetics. Surface chemistry; surface phenomena, adsorption, heterogeneous catalysis.
C454-4 Elementary Quantum Chemistry and Molecular Bonding (Pre-requisite: C244 or C264)
Foundations of quantum theory. Dynamics of microscopic systems. Elementary quantum chemistry and its application to structure and bonding in molecules and solids. Statistical thermodynamics as a model for the interpretation of macroscopic and microscopic properties of systems.
C473-3 Industrial Year IV Chemistry (Pre-requisite: C214, C234)
Sources and production of Inorganic and Organic industrial raw materials. Water utilization in energy and chemical producing industry. Synthetic polymers.
C493-3 Environmental Year IV Chemistry (Pre-requisite: C214, C224, C234)
Environment: Air, water and soil. Pollution of environment arising from gases, heavy metals, pesticides, detergents, polycyclic aromatic hydrocarbons and polychlorinated biphenyls. Its monitoring and regulation.
C4104-4 Computers in Chemistry (Pre-requisite: C264)
A practical chemistry oriented approach to computers and computation. Numerical methods of computation. Chemical applications of computers. Integrated packages of scientific software.
C4203-3 Chemistry Year IV Project (Pre-requisite: Registration in Year IV single major programme)
A research project is chosen in consultation with the head of the chemistry department and supervised by a staff member. A written report will normally be required.
Bachelor of Chemical Technology Programme
The Chemical Technology programme follows the standard chemistry single major programme currently offered up to Year II. Thereafter, the Years III and IV chemistry courses of the programme are selected from the current chemistry courses offered in Years III and IV.
Chemical Technology Courses:
CTEC312-2 Introduction to catalysis
Basic concepts in catalysis; heterogeneous catalysts, adsorption and adsorption isotherms, kinetics of heterogeneously catalysed reactions, diffusional constraints, poisoning. Catalyst preparation; zeolite synthesis, supported metal catalysts, (Co)-precipitated catalysts. Catalyst testing; ideal reactors, non-idealities in experimental reactors, external/internal mass transfer limitations. Acid catalysed reactions, metal catalysed reactions, bi-functional catalysis, partial oxidation reactions, homogeneous catalysed reactions, catalysis by enzymes. Introduction to photochemistry and photocatalysis.
CTEC323-3 Environmental Chemistry and Analysis (Pre-requisite: C224, C234)
The industrial chemistry and the environment. Introduction to the holistic approach required by industry. Sources and behaviour of anthropogenic chemical pollutant compounds in the environment. Environmental processes controlling transport and transformation and fate; physical, chemical and photochemical reactions of anthropogenic pollutant compounds in the environment.
Chemical composition of natural waters. Chemical phenomena in natural waters; Exchange of gases between water and air. Application of chemical principles to the cycling of important elements in natural waters; cycles of important elements in natural waters. The effect of anthropogenic compounds on the natural waters and freshwater ecosystems. Practicals: Measurements, recording data, calculations and report writing. Wet chemical methods (e.g. alkalinity, titrations), determination of levels of analytes/pollutants found in typical aquatic environment.
CTEC333-3 Introductory Industrial Chemistry (Pre-requisite: C 214, C 224, C 234)
A survey of the chemical industry. Chemical principles in the manufacture of inorganic and organic chemical products. Manufacture and applications of selected chemicals: fertilizers, pesticides, paints and pigments, cement, mineral acids, ceramics and refractories, electrochemical polymers, pulp and paper, agricultural, cosmetics, detergent, and petroleum products. Corrosion, high temperature creep, low temperature embrittlement.
CTEC334-4 Introduction to Materials (Pre-requisite C214, C234) Metals; extraction, processing, properties, characterization and applications. Ferrous alloys, thermal treatment. Organic polymers; synthesis, stereochemistry, copolymers, biodegradability, physical properties and industrial uses. Fundamentals of fibres and textile chemistry.
CTEC343-3 Industrial Environmental and Cleaner Production Technology (Pre-requisite: C214, C224, C 234; Co-requisite: C 314, C 334, C345)
Technologies for handling solid, liquid and airborne wastes. Waste product design and minimization of waste. Environmental technologies in agro-industries (dairies, slaughterhouses), chemical manufacturing industries. Assessment of industrial environmental activities. Specific pollutants of current interest: inorganic (e.g. mercury, NOx and SOx gases, lead, etc.) and organic (e.g. PCBs, chlorinated hydrocarbons, freons, pesticides/herbicides). Industrial sources and analytical methods of detection, control and monitoring.
CTEC353-3 Basic Electronics in Chemical Instrumentation (Pre-requisite: P190, CTEC314)
Electrical components and circuits: current-d.c. and a.c., semiconductors and semiconductor devices, power supply and regulators, readout devices. Operational amplifiers: properties of operational amplifiers (OPAMP) circuits, amplification and measurement of transducer signal, application of OPAMP to voltage and current control, application to mathematical operations, and to switching. Signal and noise: the signal-to-noise ratio, source of noise in instrumental analysis, signal-to-noise enhancement. Practicals: Measurements in circuit elements, semiconductor devices, OPAMP analog-to-digital conversion, digital multimeters, Wheatstone bridge circuits, capacitance measurements.
CTEC415-5 Synthetic Organic Chemistry (Pre-requisite: C334, CTEC314)
Polar radical and pericyclic reactions; design strategy; protective group chemistry, carbon-carbon bond forming reactions, enolates and ring syntheses, heterocyclic chemistry. Enantio-and diastereo-controlled processes and asymmetric synthesis. Free radicals in organic synthesis.
Physical organic aspects of aromatic compounds including aromaticity and structure activity correlations. Free radical and metal-catalyzed reactions. Stereochemistry and conformational analysis. Structure elucidation techniques(UV-vis, IR, NMR, GC, MS, etc.). Electrocyclic reactions, cycloaddition reactions and sigmatropic rearrangements. Organic reactive intermediates: carbanions and cations, carbenes, and free radicals. Organometallics: properties of organometallics. Principles of organometallic reactions. Catalytic organometallic process: synthesis with organometallics. Modern synthetic reactions: organo-sulfur and organo-selenium chemistry, organo-silicon chemistry. Practical: Design and synthesis of organic molecules/compounds and their characterization using spectroscopic methods and other techniques.
CTEC444-4 Applications of Physical Chemistry (Pre-requisite: C345)
Electrochemical cells, Reversible electrodes, Thermodynamics of electrochemical cells, Liquid junction potential, Measurement of pH, Membrane potential, Electrolytic cells, Electrolyte conductance, Molar conductivity, Application of Conductivity Measurements, Determination of transport numbers, Electrode kinetics, Electrochemical energy conversion and power sources, Batteries, Fuel cells, Capacitors, Fundamentals of galvanic metal deposition, Corrosion, Electrolytic processes, Anodizing, Electroplating, Metals (electrolytic production of Aluminium), Non-metals, Industrial Organic Electro-synthesis, Electrochemical use of carbon, Membrane technology, Environmental electrochemistry, Electrochemical technology for environmental treatment. (Practical: Laboratory experiments in electrochemistry)
CTEC443-3 Industrial Chemical Processes (Pre-requisite: C345)
Mass and energy balances; unit operations and unit processes, flow diagrams, batch and continuous processes, recycle, purge and bypass, heat exchange, steam tables. Phase chemistry-the phase rule, two-and three-component phase diagrams. Separation processes-distillation, solvent extraction and crystallization.
CTEC453-3 Analysis and Catalysis (Pre-requisite: CTEC314)
Sample types and preparation; chromatographic, spectroscopic and electrochemical techniques; catalytic kinetics; homogeneous catalysis; heterogeneous catalysis; enzymatic catalysis. Sampling of heterogeneous systems; use of advanced analytical instrumentation; statistical interpretation; heterogeneous and homogeneous catalysis.
CTEC455-5 Analytical Applications of Instrumental Techniques (Pre-requisite: C224/CTEC323)
Sampling and analysis: Sampling, method development, analysis and data interpretation; Spectroscopy: atomic spectroscopy and molecular spectroscopy (interpretation of combined spectra); Electroanalytical methods: potentiometry, voltammetry and stripping techniques; Thermal methods: thermo gravimetric analysis, differential thermal analysis, differential scanning calorimetry; Hyphenated methods: Interfacing analytical techniques with a focus on GC-MS, HPLC-MS, CE-MS; Applications of analytical techniques: analysis of bio-molecules, water analysis; Karl-Fisher titrations. Practical: with emphasis being placed on applied analysis, experiments on the following topics may be designed. Sampling and sample preparation, chromatography, atomic spectroscopy, molecular spectroscopy, thermal methods, electroanalytical methods, hyphenated techniques; water analysis and Karl-fisher titrations.
CTEC463-3 Chemical Engineering Principles (Pre-requisite: CTEC333)
Industrial plant; advanced mass and energy balances; fluid flow; heat transfer; agitation and mixing in liquids; reactor design; packed columns; fluidized beds; absorption/stripping; size reduction; screening; settling; cyclones.
CTEC472-2 Special Topics in Chemical Technology (Pre-requisite: Elective)
Pollution-causes, effects and prevention. Industrial biotechnology. Advanced instrumental techniques. Water pollution control. Environmental modeling. Agrochemicals. Applied electrochemistry. Introductory environmental management. Chemistry of indigenous medicinal plants of
CTEC473-3 Special Topics in Chemistry (Pre-requisite(s): C 314, C 324, C 334)
Polymer chemistry. Introductory bio-inorganic chemistry. Chemistry of natural products. Organometallic chemistry and homogeneous catalysis. Ecotoxicology. Photochemistry and its industrial applications. Advanced thermodynamics and surface chemistry.
CTEC484-4 Chemical Operations and Business Management in Chemical Technology
Plant location and layout. Production management systems: production planning; inventory control; material requirements planning (MRP), MRP II, theory of constraint (TOC) and just-in-time (JIT); supply chain management; quality assurance-ISO 9000 and 14000, benchmarking; project management-Gantt charts, critical path method. Financial management-accounting and economic appraisal. Macroeconomics and microeconomics; planning; organizing and staffing; leading; controlling; decision making; strategic and operations planning; ethics. Entrepreneurship and intrapreneurship. Managing change in organizations.
CTEC493-3 Occupational Safety and Hygiene in Chemical and Allied Industries
Recognition and identification of chemical hazards-risks and exposures, clearance mechanisms, adverse health effects; monitoring hazardous substances-sampling, quality control, health surveillance, legislation, evaluation; risk assessment-information sources, task analysis, recording and reviewing; workplace control-ventilation, respirators, noise.
CTEC404-4 Project
Students will be assigned to individual members of staff and will work on an appropriate research or project topic. During the project students will be required to attend seminars and workshops and will be encouraged to give oral presentations on the progress of their projects. Students are required to produce final reports in the form of a dissertation, which must be presented orally.
CTEC500 Industrial Attachment.
The student will be attached to a company or industry for a period of six months, where he/she will have the opportunity to transfer the knowledge from the theoretical courses to a real and practical situation.
Honours Courses:
C514-4 Advanced Inorganic Chemistry (Pre-requisite: C314 and C415)
Revision of the bonding theories and electronic spectra of transition metal compounds. Molecular orbital and ligand field approaches to the structure of transition-metal compounds. Spectra and magnetic properties related to the structure of transition metal compounds. Reaction mechanisms of Inorganic Reactions. Descriptive chemistry of lanthanides, actinides and heavy transition metals. Inorganic polymers and electron deficient compounds. Corrosion of metals.
Introduction to organometallic chemistry of the main group elements. Alkali metal (organo-lithium). Alkaline earth (organo-magnisium). Group IIIA (organo-boron, organo-aluminium). Group IVA (organo-silicon) Organometallic chemistry transition elements. The 18-valence-Electron Rule. s-donor ligands. s-donor /p-acceptor ligands. s,p-donor / p-acceptor lingands.Organometallics Catalysis. e.g Fisher-Tropsch Reaction, Hydrogenation of alkenes etc.
C524-4 Advanced Analytical Chemistry: (Pre-requisite: C424 and C334)
An advanced course in instrumental methods of chemical identification and analysis. Emphasis shall be on modern instrumentation, operating principles and interpretation of instrumental data. Discussion of advanced concepts of atomic spectroscopy, analytical separations, and electrochemical techniques followed by selection of appropriate techniques for solving analytical problems. Introduction to laboratory automation and information management.
C534-4 Advanced Organic Chemistry (Pre-requisite: C334 and c435)
Advanced introduction to reaction intermediates – carbonium, carbanion, free radicals, carbenes. Advanced reaction mechanisms – addition, elimination, substitution, condensation, oxidation reduction, aromatic eletrophilic and nucleophilic sibstitution reactions. Molecular arrangements; (a) Wagner-Murwein rearrangement (rearrangement to electron-deficient carbon. (b) pinacol-pinacolone rearrangement, (c) benzil-benzilic acid rearrangement. Rearrangement to electron-deficient nitrogen – Hoffman, Curtius, Beckamn, Schmidt and lossen rearrangements. Rearrangement to electron deficient- oxygen Bayer-Villiger reaction, Drakin reaction, cumene hydroperoxide rearrangement. Wittig, Stevens and Favorskii rearrangement. Sigmatropic rearrangemant (Claisen and
C5163-3 Molecular Spectroscopy
Electromagnetic radiation and its reaction with atoms and molecules; absorption of light by molecules. Optical spectroscopy; absorption spectroscopy; luminescence. Molecular symmetry, symmetry elements applications in chemistry, dipoles, polarizability, optical activity. General principles of experimental methods of molecular spectroscopy.
OR C5173-3 Advanced Spectroscopy (Pre-requisite: C264)
Resonance spectroscopic methods – theory and practice; nuclear magnetic resonance, electron magnetic resonance, Mossbauer (or gamma) spectroscopy. One-dimensional and two-dimensional NMR. Mass spectrometry.
C585-5 Advanced Chemical Techniques
A full year integrated laboratory course designed to acquaint the students with modern laboratory techniques in the main branches of chemistry.
Analytical section: Investigation of instrumental parameters on experimental results. Techniques covered include AA, ICP and Electroanalytical techniques.
Inorganic section: The experiments are designed to demonstrate modem techniques of preparative and diagnostic inorganic chemistry, synthesis and characterization of products by UV/Vis, IR, NMR, magnetic susceptibility, X-ray diffraction techniques.
Organic section: Syringe and inert atmosphere techniques, catalytic hydrogenation, vacuum distillation, flash column chromatography.
Reactions include aromatic nitration stereoselective hydride reduction, organocuprate substitution reaction, Grignard reactions, Friedel Crafts alkylations and others. Spectroscopic methods will routinely include FTIR, NMR, GC-MS, GC, TLC and HPLC.
Physical section: Investigation of molecular structure by several techniques; electroanalytical techniques, thermal analysis, X-ray diffraction techniques and dipole measurements.
C5143-3 Chemical Kinetics and Reaction Mechanisms
Review of reactions and reaction rates. Reactions with simple kinetic form. Experimental techniques in reaction kinetics-flow methods and rapid reaction methods. Reversible and concurrent reactions. Consecutive reactions; the steady state and other approximations. Complex mechanisms and intermediates, deduction of reaction mechanisms. Transition state theory and microscopic reversibility. Chain reactions and Oscillating reactions. Reactions in solutions. Extra-kinetic probes of mechanism.
C5206-6 Chemistry Year V Project
Research project chosen by students and supervisors in consultation with the head of the department. Students are expected to spend the equivalent of 6-8 hrs of laboratory work per week, both semesters.
C543-3 Statistical Thermodynamics, Elective, (Pre-requisite: C345)
A course providing an insight into statistical foundations of thermodynamics, link between the structure of molecules and bulk properties and explanation to the theory of chemical equilibrium.
C553-3 Introduction to Quantum Chemistry, Elective, (Pre-requisite: C454)
Postulates and principles of quantum mechanics. Approximate methods of solving Schrödinger equation: variation principle, perturbation theory. Theory of atoms. Hartree-Fock approximation. Approximate atomic orbitals. Theory of molecules. MO and VB approaches. Roothaan equations. Beyond HF-Scheme: electron correlation, configuration interaction. Relativistic correlations.
C573-3 Industrial Year V Chemistry, Elective, (Pre-requisite: C473 OR C415 and C435)
Sources and production of industrial raw materials. Synthetic polymers, paper and textiles, detergents, agrochemicals and food additives.
C5003-3 Application of Computers in Chemistry, Elective, (Pre-requisite: C454)
A course dealing with advanced data processing, numerical techniques and computational aspects of chemistry including molecular mechanics, a selection of semi-empirical and abinitio quantum chemistry methods.
C5113-3 Introductory Bio-Inorganic Chemistry, Elective, (Pre-requisite: C415)
Functional concepts in Bio-Inorganic chemistry. The chemistry of macro-molecules and their metabolism. Enzymes (kinetics and mechanisms).
MSC Courses
A directed literature investigation of a topic producing a written report and an oral presentation.
C611-4 Advanced Inorganic Chemistry
Review of the valence bond, crystal field, ligand field, and molecular orbital theories of bonding in metal complexes. Electronic spectra and magnetic properties of transition metal complexes. Molecular symmetry and group theory.
C612-4 Reactions and Mechanisms of Inorganic Complexes
Substitution reactions: classification of mechanisms, substitution in square planar and octahedral complexes, rate laws and their interpretations; mechanisms of reduction-oxidation reaction; oxidative-addition and migration (insertion) reactions.
(one practical/week)
C613-3 Descriptive Chemistry of the Elements
Review of the s- and p-block elements. The general properties of transition metals. Extraction and uses and oxidation states. Physical and chemical properties. Reactions and separation of the lanthanides.
C614-3 Organometallic Chemistry
Review of the organometallic chemistry of the main group elements. Basic concepts of organometallic chemistry of the transition elements: the 18-valence electron rule; σ-donor, π-donor and π-acceptor ligands. Bonding between metal atoms and organic π-systems. Spectral analysis and characterisation of organometallic complexes. Applications of organometallic compounds of the transition elements in synthesis and catalysis.
C615-3 Bioinorganic Chemistry
Inorganic composition of cells. Transport, transfer and transcription in biological systems. Metal ions in biological catalytic processes: acid-base catalysis, enzymes. Sensors – iron proteins as sensors; copper and zinc levels sensing. Biomineralisation. Chemistry of elements in medicine.
C616-3 Chemistry of Inorganic Materials
Synthesis of inorganic materials. Framework structures. Inorganic pigments. Molecular materials. Chemistry and technology of glasses: structure, physical properties, compositional effects. Crystallization and phase separation. Nanomaterials: characterisation and fabrication; artificially layered materials; self-assembled nanostructures.
C617-2
C621-4 Modern Separations and Analytical Spectroscopy
Review of theory and instrumentation of separation and spectroscopic methods with emphasis on applications in quantitative analysis and structural elucidations. Separations: PC, TLC, GC, HPLC, SFC, and CE. Spectroscopy: Optical activity, Ultraviolet/visible, Infrared, Luminescence, Raman, EPR, Mössbauer, NMR and Mass spectrometry.
C622-4 Sampling and Analytical Methods Development
Techniques and devices for sampling of gases, liquids and solids. Sample treatment including digestion, isolation, concentration, derivatization and fractionation of analytes. Analytical methods development and validation. Automatic and flow injection analysis.
(one practical/week)
C623-4 Physical Methods of Characterization
A survey of principles, instrumentation, and applications of surface characterization methods: X-ray diffraction, fluorescence, SEM, SPM, TEM, AES and ESCA; thermal and synchrotron radiation methods.
C624-2 Statistics for Analytical Chemistry
Probability, sampling, regression analysis, experimental design, data analysis and signal enhancement. Statistics used in chemometrics; predictive models: regression; process optimization, numerical methods, fundamentals of chemical process control and good laboratory practices (GLP).
C625-3 Electroanalytical Chemistry
Review of Redox equilibria and electroanalytical instrumentation. Potentiometry and potentiometric titrations. Controlled potential and constant current methods: voltammetry (including polarography, cyclic, hydrodynamic, and striping techniques), coulometry, electrogravimetry, electrogravimetric and coulometric titrations.
C626-3 Bioanalysis and Laboratory Management
Clinical and immuno-chemistry techniques, biosensors, carbohydrate analysis, genomics and proteomics. Applications of hyphenated techniques in bioanalysis. Laboratory information management systems, validation, quality assurance, accreditation and in-process analysis.
C627-3 Forensic and Materials Analysis
Overview of characterization and analysis techniques used in research and routine analysis of materials in forensic science, colloidal science and polymer science and technology.
C628-3 Modern NMR Spectroscopy
Theoretical and practical training on operation, management, parameters optimization, spectral acquisition, data processing and interpretation, chemical structure determination and reaction dynamics using 1- and 2-D techniques: Proton heteronuclei, COSY, HSQC, HMBC, NOESY, EXSY, TOCSY, DEPT, INADEQUATE.
(one practical/week)
C631–4 Advanced Organic Chemistry
Advanced introduction to reaction intermediates; Advanced reaction mechanisms; molecular rearrangements; heterocyclic chemistry
C632–2 Practical Organic Chemistry
Synthesis, separation and structure elucidation of Organic Molecules
(two practicals per week)
C633–3 Synthesis in Action
Retrosynthetic analysis, chemoselectivity, protection of groups; synthesis of peptides and aromatic heterocyclics; asymmetric synthesis and solid phase chemistry
C634–3 Mechanisms in Biological Chemistry
Organic mechanisms with enzymes, co-enzymes, vitamins, NADH; reductive amination, deamination, carboxylation and decarboxylation, enol chemistry, redox reactions, and the chemistry of amino acids.
C635–3 Polymers
Oligomers, polyamides, polyesters, polycarbonates, polyurethane foams, alkene polymers, rubber and peptides.
C637–3 Natural Products Chemistry
Natural Products: biogenesis and biosynthesis of natural products; Survey of important classes of natural products; NMR and spectroscopic analysis of selected natural products
C638-3 Physical Organic Chemistry
Approximate MO theory, frontier orbitals. Correlation of structure with reactivity: linear free energy relationships, Hammett equation, theories of substituent effects. Solvent and steric effects. Effect of structure on acidity and basicity, electrophilicity and nucleophilicity. Characterization of types of acid and base catalysis. Effect of structure on substitution, elimination, polar addition, intramolecular, radical, and pericyclic reactions.
C641-4 Quantum Chemistry and Molecular Spectroscopy
Schrödinger’s equation, wavefunctions, atomic theory, molecular orbital theory; theory of spectroscopy; rotational, vibrational and electronic spectroscopy.
C642-3 Advanced Chemical Kinetics
Elementary reaction steps, steady state theory and applications, chain reactions and explosions; bimolecular collision theory; transition state theory; reactions in solution; photochemical kinetics.
C643-3 Statistical Thermodynamics
Partition functions, energy and entropy; canonical partition functions and thermodynamic quantities: mean energy, heat capacity, entropy, and free energy. Partition functions and equilibrium constants.
C644-4 Electrochemistry: Theory and Applications
Thermodynamics in electrochemistry; The electrical double layer; Electrode kinetics; Mass transport; Electrocatalysis; Spectroelectrochemistry; Corrosion; Electrochemical techniques and instrumentation. (one practical/week)
C645-3 Computational Chemistry
The Born-Oppenheimer and orbital approximations. Pauli Principle and determinental wavefunctions. Variational principle and the self-consistent field method. Principles of Hartree-Fock procedure and diagonalization. Differential overlap integrals and semi-empirical methods; ab initio calculations. Electron correlation and configuration interaction. Types of basis sets. Geometry optimisation. Mulliken population analysis. Vibrational modes. Practical work using Gaussian: devising input and interpreting outputs. (one practical/week)
C646-3 Colloids & Surface Chemistry
Matter in the colloidal state: the main types of colloids; Characteristic phenomena in colloid systems and dispersions; Preparation methods for colloids; Kinetic and optical properties of colloids. Thermodynamics of interfacial systems. Liquid-Gas and Liquid-Liquid interfaces; The Solid-Gas interface; Adsorption isotherms, The Solid-Liquid interface; Charged interfaces. Inter-particle forces in colloidal systems: theory of Lifshitz and double layer theory of colloid stability, DLVO theory; Emulsions and foams. Surfactants: micelles; surface films.
C681-2 Experimental Techniques
A collection of practicals and mini-projects introducing the essential techniques, instruments, and procedures required for success in advanced chemistry. (two practicals/week)
C693-3 Environmental Chemistry
Review of the sources, fate, and reactivity of compounds in natural and polluted environments. Environmental implications of energy utilization. Chemistry of the atmosphere, hydrosphere, and lithosphere and environmental analytical techniques; topics include climate change, air pollution, stratospheric ozone depletion, pollution and treatment of water sources, and the utilization of pesticides.